Pharmacotherapy has always been an integral part of healthcare system and will remain so in the future. With the advent of innovative interventions its role has become even more critical and requires the continuous availability of quality, effective and affordable pharmaceuticals. Pharmaceutical Fund and Supply Agency is the public body entrusted with this role in Ethiopia. Though the Agency has been working hard to insure the continuous availability of needed pharmaceuticals at service delivery points, there is still huge gap between demand and supply in pharmaceuticals. So far, there is no defined and agreed upon list of pharmaceuticals that the Agency procures and avails to public health facilities. As part of its transformation, the Agency has been working on preparing a defined list of pharmaceuticals that will guide its procurement and supply. After series of consultations with stakeholders involving relevant experts in each area from health facilities, FMOH, RHBs, EPHI, EHIA, development partners and the Agency, first edition of the list is now ready for use